TY - JOUR
T1 - Towards a youth mental health paradigm
T2 - a perspective and roadmap
AU - Uhlhaas, Peter J.
AU - Davey, Christopher G.
AU - Mehta, Urvakhsh Meherwan
AU - Shah, Jai
AU - Torous, John
AU - Allen, Nicholas B.
AU - Avenevoli, Shelli
AU - Bella-Awusah, Tolulope
AU - Chanen, Andrew
AU - Chen, Eric Y.H.
AU - Correll, Christoph U.
AU - Do, Kim Q.
AU - Fisher, Helen L.
AU - Frangou, Sophia
AU - Hickie, Ian B.
AU - Keshavan, Matcheri S.
AU - Konrad, Kerstin
AU - Lee, Francis S.
AU - Liu, Cindy H.
AU - Luna, Beatriz
AU - McGorry, Patrick D.
AU - Meyer-Lindenberg, Andreas
AU - Nordentoft, Merete
AU - Öngür, Dost
AU - Patton, George C.
AU - Paus, Tomáš
AU - Reininghaus, Ulrich
AU - Sawa, Akira
AU - Schoenbaum, Michael
AU - Schumann, Gunter
AU - Srihari, Vinod H.
AU - Susser, Ezra
AU - Verma, Swapna K.
AU - Woo, T. Wilson
AU - Yang, Lawrence H.
AU - Yung, Alison R.
AU - Wood, Stephen J.
N1 - Publisher Copyright:
© 2023, The Author(s).
PY - 2023/8
Y1 - 2023/8
N2 - Most mental disorders have a typical onset between 12 and 25 years of age, highlighting the importance of this period for the pathogenesis, diagnosis, and treatment of mental ill-health. This perspective addresses interactions between risk and protective factors and brain development as key pillars accounting for the emergence of psychopathology in youth. Moreover, we propose that novel approaches towards early diagnosis and interventions are required that reflect the evolution of emerging psychopathology, the importance of novel service models, and knowledge exchange between science and practitioners. Taken together, we propose a transformative early intervention paradigm for research and clinical care that could significantly enhance mental health in young people and initiate a shift towards the prevention of severe mental disorders.
AB - Most mental disorders have a typical onset between 12 and 25 years of age, highlighting the importance of this period for the pathogenesis, diagnosis, and treatment of mental ill-health. This perspective addresses interactions between risk and protective factors and brain development as key pillars accounting for the emergence of psychopathology in youth. Moreover, we propose that novel approaches towards early diagnosis and interventions are required that reflect the evolution of emerging psychopathology, the importance of novel service models, and knowledge exchange between science and practitioners. Taken together, we propose a transformative early intervention paradigm for research and clinical care that could significantly enhance mental health in young people and initiate a shift towards the prevention of severe mental disorders.
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U2 - 10.1038/s41380-023-02202-z
DO - 10.1038/s41380-023-02202-z
M3 - Review article
C2 - 37580524
AN - SCOPUS:85168659890
SN - 1359-4184
VL - 28
SP - 3171
EP - 3181
JO - Molecular Psychiatry
JF - Molecular Psychiatry
IS - 8
ER -