Towards identifying genes underlying ecologically relevant traits in Arabidopsis thaliana

Joy Bergelson, Fabrice Roux

Research output: Contribution to journalReview articlepeer-review


A major challenge in evolutionary biology and plant breeding is to identify the genetic basis of complex quantitative traits, including those that contribute to adaptive variation. Here we review the development of new methods and resources to fine-map intraspecific genetic variation that underlies natural phenotypic variation in plants. In particular, the analysis of 107 quantitative traits reported in the first genome-wide association mapping study in Arabidopsis thaliana sets the stage for an exciting time in our understanding of plant adaptation. We also argue for the need to place phenotypeĝ€ "genotype association studies in an ecological context if one is to predict the evolutionary trajectories of plant species.

Original languageEnglish (US)
Pages (from-to)867-879
Number of pages13
JournalNature Reviews Genetics
Issue number12
StatePublished - Dec 2010

ASJC Scopus subject areas

  • Molecular Biology
  • Genetics
  • Genetics(clinical)


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