Translational and clinical applications of salivary diagnostics.

W. V. Giannobile, J. T. McDevitt, R. S. Niedbala, D. Malamud

Research output: Contribution to journalArticlepeer-review


There have been significant advances in techniques for the detection of biomarker signals in the oral cavity (e.g., ELISAs for proteins, PCR for RNA and DNA) as well as the engineering and development of microfluidic approaches to make oral-based point-of-care (POC) methods for the diagnosis for both local and systemic conditions a reality. In this section, we focus on three such approaches, namely, periodontal disease management, early markers for systemic diseases, and salivary markers useful for pharmacogenomic studies. Novel approaches using non-invasive, salivary samples and user-friendly devices offer results that are as sensitive and specific as laboratory-based analyses using blood or urine.

Original languageEnglish (US)
Pages (from-to)375-380
Number of pages6
JournalAdvances in dental research
Issue number4
StatePublished - Oct 2011

ASJC Scopus subject areas

  • General Medicine


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