Transport and diffusion calculations on MRI-generated data

Andreas H. Hielscher, Raymond E. Alcouffe, Randall L. Barbour

    Research output: Contribution to journalConference articlepeer-review


    In this study we analyze the limits of the diffusion approximation to the Boltzmann transport equation for photon propagation in the human brain. Two dimensional slices through the head are obtained with the method of magnetic resonance imaging (MRI). Based on these images we assign optical properties to different regions of the brain. A finite-difference transport/diffusion code is then used to calculate the fluence throughout the head. Differences between diffusion and transport calculations occur especially in void-like spaces and regions where the absorption coefficient is comparable to the reduced scattering coefficient.

    Original languageEnglish (US)
    Pages (from-to)500-508
    Number of pages9
    JournalProceedings of SPIE - The International Society for Optical Engineering
    StatePublished - 1997
    EventProceedings of Optical Tomography and Spectroscopy of Tissue: Theory, Instrumentation, Model and Human Studies II - San Jose, CA, United States
    Duration: Feb 9 1997Feb 12 1997


    • Brain
    • Diffusion theory
    • Discrete ordinate
    • Finite difference
    • Magnetic resonance imaging
    • Photon propagation in tissues
    • Transport theory

    ASJC Scopus subject areas

    • Electronic, Optical and Magnetic Materials
    • Condensed Matter Physics
    • Computer Science Applications
    • Applied Mathematics
    • Electrical and Electronic Engineering


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