Abstract
A new therapeutic approach involves the discovery by the "Stony Brook group," that tetracyclines, but not other antibiotics, can inhibit host-derived collagen-destructive enzymes. This newly discovered property of tetracyclines is unrelated to the antimicrobial activity of these drugs. Examples support the hypothesis that this unexpected property of tetracyclines provides a new approach to treating periodontal diseases as well as a variety of medical disorders.
Original language | English (US) |
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Pages (from-to) | 163-169; discussion 169-171 |
Journal | Journal of the American Dental Association (1939) |
Volume | 125 |
Issue number | 2 |
DOIs | |
State | Published - Feb 1994 |
ASJC Scopus subject areas
- General Dentistry