Trends in mortality, length of stay, and hospital charges associated with health care–associated infections, 2006-2012

Sherry Glied, Bevin Cohen, Jianfang Liu, Matthew Neidell, Elaine Larson

Research output: Contribution to journalArticlepeer-review


Background Many factors associated with hospital-acquired infections (HAIs), including reimbursement policies, drug prices, practice patterns, and the distribution of organisms causing infections, change over time. We examined whether outcomes, including mortality, length of stay (LOS), daily charges, and total charges associated with HAIs, changed during 2006-2012. Methods Electronic data on adults discharged from 2 tertiary-quaternary hospitals and 1 community hospital during 2006-2012 were collected retrospectively. Computerized algorithms identified infections using laboratory and administrative codes. Propensity scores were used to match cases with uninfected controls. Differences in mortality, LOS, daily charges, and total charges were modeled against infection status and time period (2006-2008 vs 2009-2012), including interaction for infection status by time period. Results Among 352,077 discharges, 24,466 HAIs were detected. There was no significant change in mortality. LOS declined only for bloodstream infections (3-day reduction; P < 0.01). Daily charges rose 4% for urinary tract infections but did not change significantly for other HAIs. Total charges declined by 11% for bloodstream infections and 13% for pneumonia. Conclusions We found no appreciable or consistent improvement in HAI mortality or LOS during 2006-2012. Costs of bloodstream infections and pneumonia have declined, with most of the change occurring before 2008.

Original languageEnglish (US)
Pages (from-to)983-989
Number of pages7
JournalAmerican Journal of Infection Control
Issue number9
StatePublished - Sep 1 2016


  • Health care–associated infections
  • value-based purchasing

ASJC Scopus subject areas

  • Epidemiology
  • Health Policy
  • Public Health, Environmental and Occupational Health
  • Infectious Diseases


Dive into the research topics of 'Trends in mortality, length of stay, and hospital charges associated with health care–associated infections, 2006-2012'. Together they form a unique fingerprint.

Cite this