Two dimensional PNA/DNA arrays: Estimating the helicity of unusual nucleic acid polymers

Philip S. Lukeman; Alexander C. Mittal; Nadrian C. Seeman

doi:10.1039/b401103a

Two dimensional PNA/DNA arrays: Estimating the helicity of unusual nucleic acid polymers

Philip S. Lukeman, Alexander C. Mittal, Nadrian C. Seeman

Chemistry

Research output: Contribution to journal › Article › peer-review

Abstract

We extend the generality of nucleic acid-based structural nanotechnology by incorporating non-natural nucleic acids into a DNA double crossover (DX) molecule; visualizing two-dimensional arrays of these DX molecules by Atomic Force Microscopy (AFM) enables us to measure the helical repeat of any heteroduplex sequence capable of forming the outer arms of a DX.

Original language	English (US)
Pages (from-to)	1694-1695
Number of pages	2
Journal	Chemical Communications
Volume	4
Issue number	15
DOIs	https://doi.org/10.1039/b401103a
State	Published - 2004

ASJC Scopus subject areas

Catalysis
Electronic, Optical and Magnetic Materials
Ceramics and Composites
General Chemistry
Surfaces, Coatings and Films
Metals and Alloys
Materials Chemistry

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10.1039/b401103a

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abstract = "We extend the generality of nucleic acid-based structural nanotechnology by incorporating non-natural nucleic acids into a DNA double crossover (DX) molecule; visualizing two-dimensional arrays of these DX molecules by Atomic Force Microscopy (AFM) enables us to measure the helical repeat of any heteroduplex sequence capable of forming the outer arms of a DX.",

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AB - We extend the generality of nucleic acid-based structural nanotechnology by incorporating non-natural nucleic acids into a DNA double crossover (DX) molecule; visualizing two-dimensional arrays of these DX molecules by Atomic Force Microscopy (AFM) enables us to measure the helical repeat of any heteroduplex sequence capable of forming the outer arms of a DX.

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Two dimensional PNA/DNA arrays: Estimating the helicity of unusual nucleic acid polymers

Abstract

ASJC Scopus subject areas

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