Two dimensional PNA/DNA arrays: Estimating the helicity of unusual nucleic acid polymers

Philip S. Lukeman, Alexander C. Mittal, Nadrian C. Seeman

Research output: Contribution to journalArticle

Abstract

We extend the generality of nucleic acid-based structural nanotechnology by incorporating non-natural nucleic acids into a DNA double crossover (DX) molecule; visualizing two-dimensional arrays of these DX molecules by Atomic Force Microscopy (AFM) enables us to measure the helical repeat of any heteroduplex sequence capable of forming the outer arms of a DX.

Original languageEnglish (US)
Pages (from-to)1694-1695
Number of pages2
JournalChemical Communications
Volume4
Issue number15
DOIs
StatePublished - 2004

ASJC Scopus subject areas

  • Catalysis
  • Electronic, Optical and Magnetic Materials
  • Ceramics and Composites
  • Chemistry(all)
  • Surfaces, Coatings and Films
  • Metals and Alloys
  • Materials Chemistry

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