Ultrafast Z-spectroscopy for 129Xe NMR-based sensors

Céline Boutin, Estelle Léonce, Thierry Brotin, Alexej Jerschow, Patrick Berthault

Research output: Contribution to journalArticlepeer-review

Abstract

When working with hyperpolarized species, it is often difficult to maintain a stable level of magnetization over consecutive experiments, which renders their detection at the trace level cumbersome, even when combined with chemical exchange saturation transfer (CEST). We report herein the use of ultrafast Z-spectroscopy as a powerful means to detect low concentrations of 129Xe NMR-based sensors and to measure the in-out xenon exchange. Modifications of the original sequence enable a multiplexed detection of several sensors, as well as the extraction of the exchange buildup rate constant in a single-shot fashion.

Original languageEnglish (US)
Pages (from-to)4172-4176
Number of pages5
JournalJournal of Physical Chemistry Letters
Volume4
Issue number23
DOIs
StatePublished - Dec 5 2013

Keywords

  • biosensors
  • exchange
  • hyperpolarization
  • magnetic resonance
  • sensitivity

ASJC Scopus subject areas

  • Materials Science(all)
  • Physical and Theoretical Chemistry

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