Ultrahigh Resolution Ophthalmic Imaging with Optical Coherence Tomography

Ravi K. Ghanta, Wolfgang Drexler, Uwe Margner, Franz Kärtner, Erich P. Ippen, James G. Fujimoto, Joel S. Schuman, Sven Burseil

Research output: Chapter in Book/Report/Conference proceedingConference contribution


In vivo ultrahigh resolution, spectroscopic optical coherence tomography (OCT) with 3μm axial resolution allows for an unprecedented visualization of microstructure relevant to pathology in the anterior eye and retina. The visualization of retinal morphology and intraretinal structures shown here demonstrate the potential for this technique to identify early structural and functional changes associated with retinal diseases, such as diabetic retinopathy and glaucoma. Ultrahigh resolution OCT allows delineation of corneal morphology, including the corneal epithelium and endothelium. Ultrahigh resolution OCT also allows for the imaging of animal models of disease, such as transgenic mice, providing a powerful research tool to better understand disease pathogenesis and evaluate therapies.

Original languageEnglish (US)
Title of host publicationBiomedical Optical Spectroscopy and Diagnostics, BOSD 2000
PublisherOptica Publishing Group (formerly OSA)
Number of pages3
ISBN (Electronic)155752632X
StatePublished - 2000
EventBiomedical Optical Spectroscopy and Diagnostics, BOSD 2000 - Miami Beach, United States
Duration: Apr 2 2000 → …

Publication series

NameOptics InfoBase Conference Papers
ISSN (Electronic)2162-2701


ConferenceBiomedical Optical Spectroscopy and Diagnostics, BOSD 2000
Country/TerritoryUnited States
CityMiami Beach
Period4/2/00 → …

ASJC Scopus subject areas

  • Electronic, Optical and Magnetic Materials
  • Mechanics of Materials


Dive into the research topics of 'Ultrahigh Resolution Ophthalmic Imaging with Optical Coherence Tomography'. Together they form a unique fingerprint.

Cite this