Ultrahigh Resolution Ophthalmic Imaging with Optical Coherence Tomography

Ravi K. Ghanta, Wolfgang Drexler, Uwe Margner, Franz Kärtner, Erich P. Ippen, James G. Fujimoto, Joel S. Schuman, Sven Burseil

    Research output: Chapter in Book/Report/Conference proceedingConference contribution


    In vivo ultrahigh resolution, spectroscopic optical coherence tomography (OCT) with 3μm axial resolution allows for an unprecedented visualization of microstructure relevant to pathology in the anterior eye and retina. The visualization of retinal morphology and intraretinal structures shown here demonstrate the potential for this technique to identify early structural and functional changes associated with retinal diseases, such as diabetic retinopathy and glaucoma. Ultrahigh resolution OCT allows delineation of corneal morphology, including the corneal epithelium and endothelium. Ultrahigh resolution OCT also allows for the imaging of animal models of disease, such as transgenic mice, providing a powerful research tool to better understand disease pathogenesis and evaluate therapies.

    Original languageEnglish (US)
    Title of host publicationBiomedical Optical Spectroscopy and Diagnostics, BOSD 2000
    PublisherOptica Publishing Group (formerly OSA)
    Number of pages3
    ISBN (Electronic)9781557528209
    StatePublished - 2000
    EventBiomedical Optical Spectroscopy and Diagnostics, BOSD 2000 - Miami Beach, United States
    Duration: Apr 2 2000 → …

    Publication series

    NameOptics InfoBase Conference Papers


    ConferenceBiomedical Optical Spectroscopy and Diagnostics, BOSD 2000
    Country/TerritoryUnited States
    CityMiami Beach
    Period4/2/00 → …

    ASJC Scopus subject areas

    • Electronic, Optical and Magnetic Materials
    • Mechanics of Materials


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