Ultrahigh-resolution optical coherence tomography in glaucoma

Gadi Wollstein, Leila A. Paunescu, Tony H. Ko, James G. Fujimoto, Andrew Kowalevicz, Ingmar Hartl, Siobahn Beaton, Hiroshi Ishikawa, Cynthia Mattox, Omah Singh, Jay Duker, Wolfgang Drexler, Joel S. Schuman

Research output: Contribution to journalArticlepeer-review


Objective: Optical coherence tomography (OCT) has been shown to be a valuable tool in glaucoma assessment. We investigated a new ultrahigh-resolution OCT (UHR-OCT) imaging system in glaucoma patients and compared the findings with those obtained by conventional-resolution OCT. Design: Retrospective comparative case series. Participants: A normal subject and 4 glaucoma patients representing various stages of glaucomatous damage. Testing: All participants were scanned with StratusOCT (axial resolution of ∼10 μm) and UHR-OCT (axial resolution of ∼3 μm) at the same visit. Main Outcome Measure: Comparison of OCT findings detected with StratusOCT and UHR-OCT. Results: Ultrahigh-resolution OCT provides a detailed cross-sectional view of the scanned retinal area that allows differentiation between retinal layers. These UHR images were markedly better than those obtained by the conventional-resolution OCT. Conclusions: Ultrahigh-resolution OCT provides high-resolution images of the ocular posterior segment, which improves the ability to detect retinal abnormalities due to glaucoma.

Original languageEnglish (US)
Pages (from-to)229-237
Number of pages9
Issue number2
StatePublished - Feb 2005

ASJC Scopus subject areas

  • Ophthalmology


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