Ultrahigh-resolution optical coherence tomography in glaucoma

Objective: Optical coherence tomography (OCT) has been shown to be a valuable tool in glaucoma assessment. We investigated a new ultrahigh-resolution OCT (UHR-OCT) imaging system in glaucoma patients and compared the findings with those obtained by conventional-resolution OCT. Design: Retrospective comparative case series. Participants: A normal subject and 4 glaucoma patients representing various stages of glaucomatous damage. Testing: All participants were scanned with StratusOCT (axial resolution of ∼10 μm) and UHR-OCT (axial resolution of ∼3 μm) at the same visit. Main Outcome Measure: Comparison of OCT findings detected with StratusOCT and UHR-OCT. Results: Ultrahigh-resolution OCT provides a detailed cross-sectional view of the scanned retinal area that allows differentiation between retinal layers. These UHR images were markedly better than those obtained by the conventional-resolution OCT. Conclusions: Ultrahigh-resolution OCT provides high-resolution images of the ocular posterior segment, which improves the ability to detect retinal abnormalities due to glaucoma.