TY - JOUR
T1 - Unit responses evoked in the amygdala and striatum by electrical stimulation of the medial geniculate body
AU - Clugnet, Marie Christine
AU - LeDoux, Joseph E.
AU - Morrison, Shaun F.
PY - 1990
Y1 - 1990
N2 - Unit activity was recorded from cells and cell clusters in the amygdala and striatum in response to electrical stimulation of the medial geniculate body (MGB) in rats anesthetized with chloral hydrate. Responses were mostly excitatory and were evoked against a relatively silent background (i.e., the units seldom fired between stimuli). The shortest latency responses were recorded in the caudate putamen (CPU), lateral amygdaloid nucleus (AL), and amygdalostriatal transition area (AST). Longer latency responses were obtained from neurons in the basolateral (ABL), basomedial (ABM), and central (ACE) nuclei of the amygdala. Moreover, while responses were evoked in AL, AST, and CPU with 300-500 MA stimuli delivered once every 10 sec, more intense and higher-frequency stimuli were required to obtain responses in ABL, ABM, and ACE. These findings are consistent with anatomical tracing studies showing that AL, AST, and CPU receive direct projections from the MGB and related acoustic processing areas of the thalamus but that ACE, ABL, and ABM do not.
AB - Unit activity was recorded from cells and cell clusters in the amygdala and striatum in response to electrical stimulation of the medial geniculate body (MGB) in rats anesthetized with chloral hydrate. Responses were mostly excitatory and were evoked against a relatively silent background (i.e., the units seldom fired between stimuli). The shortest latency responses were recorded in the caudate putamen (CPU), lateral amygdaloid nucleus (AL), and amygdalostriatal transition area (AST). Longer latency responses were obtained from neurons in the basolateral (ABL), basomedial (ABM), and central (ACE) nuclei of the amygdala. Moreover, while responses were evoked in AL, AST, and CPU with 300-500 MA stimuli delivered once every 10 sec, more intense and higher-frequency stimuli were required to obtain responses in ABL, ABM, and ACE. These findings are consistent with anatomical tracing studies showing that AL, AST, and CPU receive direct projections from the MGB and related acoustic processing areas of the thalamus but that ACE, ABL, and ABM do not.
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U2 - 10.1523/jneurosci.10-04-01055.1990
DO - 10.1523/jneurosci.10-04-01055.1990
M3 - Article
C2 - 2329366
AN - SCOPUS:0025411360
SN - 0270-6474
VL - 10
SP - 1055
EP - 1061
JO - Journal of Neuroscience
JF - Journal of Neuroscience
IS - 4
ER -