Unsuspected Cocaine Exposure in Young Children

Sigmund J. Kharasch, Deborah Glotzer, Robert Vinci, Michael Weitzman, James Sargent

Research output: Contribution to journalArticlepeer-review


To determine the prevalence of cocaine exposure among preschool children with clinically unsuspected signs and/or symptoms. Prevalence study. Pediatric emergency department in an inner-city hospital. 250 children aged 2 weeks to 5 years who underwent urine assays for cocaine prior to discharge from the emergency department. None. Six (2.4%) of the 250 urine assays (95% confidence interval, 0.5% to 4.3%) were positive for benzoylecgonine, the major urinary cocaine metabolite. Four of the positive urine assays were from children younger than 1 year and all children with positive urine assays were younger than 24 months. None of these children presented with a complaint or was identified as having clinical problems currently associated with childhood exposure to cocaine. Possible exposure routes include breast-feeding, intentional administration, accidental ingestion of cocaine or cocaine-contaminated household dust via normal hand-to-mouth activity, and passive inhalation of “crack” vapors. Among the inner-city children served by this hospital, significant numbers of infants and young children are being exposed to cocaine, and this exposure occurs in a clinically unsuspected population.

Original languageEnglish (US)
Pages (from-to)204-206
Number of pages3
JournalAmerican Journal of Diseases of Children
Issue number2
StatePublished - Feb 1991

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health


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