TY - JOUR
T1 - Updates in the Management of Patients with Obstructive Sleep Apnea
AU - Davies, Adrian
AU - Jaganathan, Nikhil
AU - Cho, Yeilim
AU - Liu, Xiaoyue
AU - Healy, Sara J.
AU - Kwon, Younghoon
AU - Healy, William J.
N1 - Publisher Copyright:
Copyright © 2025 by The Southern Medical Association.
PY - 2025/6
Y1 - 2025/6
N2 - Obstructive sleep apnea (OSA), a condition with high prevalence, is characterized by reduced dilatory function of pharyngeal muscles, which can be influenced by upper airway narrowing, dilator muscle dysfunction, respiratory dysfunction, and genetics. Three of the most clinically important phenotypes of OSA include disturbed sleep, excessive sleepiness, and minimal symptoms, with varying implications for management and morbidity. This article reviews current perspectives on these OSA phenotypes, as well as the process of confirming a diagnosis of OSA. Lastly, this article delineates various current and future OSA therapy approaches through review and analysis of the existing literature with discussion on the outlook for OSA treatment.
AB - Obstructive sleep apnea (OSA), a condition with high prevalence, is characterized by reduced dilatory function of pharyngeal muscles, which can be influenced by upper airway narrowing, dilator muscle dysfunction, respiratory dysfunction, and genetics. Three of the most clinically important phenotypes of OSA include disturbed sleep, excessive sleepiness, and minimal symptoms, with varying implications for management and morbidity. This article reviews current perspectives on these OSA phenotypes, as well as the process of confirming a diagnosis of OSA. Lastly, this article delineates various current and future OSA therapy approaches through review and analysis of the existing literature with discussion on the outlook for OSA treatment.
KW - phenotypes
KW - sleep
KW - sleep apnea, central
KW - sleep apnea, obstructive
KW - therapy
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U2 - 10.14423/SMJ.0000000000001838
DO - 10.14423/SMJ.0000000000001838
M3 - Review article
C2 - 40456550
AN - SCOPUS:105005958623
SN - 0038-4348
VL - 118
SP - 349
EP - 352
JO - Southern Medical Journal
JF - Southern Medical Journal
IS - 6
ER -