We prove new upper bounds on the tolerable level of noise in a quantum circuit. Our circuits consist of unitary k-qubit gates each of whose input wires is subject to depolarizing noise of strength p, and arbitrary one-qubit gates that are essentially noise-free. We assume the output of the circuit is the result of measuring some designated qubit in the final state. Our main result is that for p > 1 - Θ(1/√k), the output of any such circuit of large enough depth is essentially independent of its input, thereby making the circuit useless. For the important special case of k = 2, our bound is p > 35.7%. Moreover, if the only gate on more than one qubit is the CNOT, then our bound becomes 29.3%. These bounds on p are notably better than previous bounds, yet incomparable because of the somewhat different circuit model that we are using. Our main technique is a Pauli basis decomposition, which we believe should lead to further progress in deriving such bounds.