TY - JOUR
T1 - Variational image segmentation for endoscopic human colonic aberrant crypt foci
AU - Figueiredo, Isabel N.
AU - Figueiredo, Pedro N.
AU - Stadler, Georg
AU - Ghattas, Omar
AU - Araujo, Adérito
N1 - Funding Information:
Manuscript received May 27, 2009; revised October 23, 2009; accepted October 26, 2009. First published November 17, 2009; current version published April 02, 2010. This work was supported in part by the University of Texas at Austin–Portugal Program under Research Project UTAustin/MAT/0009/2008. Asterisk indicates corresponding author. *I. N. Figueiredo is with the Centre for Mathematics, Department of Mathematics, University of Coimbra, 3001-454 Coimbra, Portugal (e-mail: [email protected]).
PY - 2010/4
Y1 - 2010/4
N2 - The aim of this paper is to introduce a variational image segmentation method for assessing the aberrant crypt foci (ACF) in the human colon captured in vivo by endoscopy. ACF are thought to be precursors for colorectal cancer, and therefore their early detection may play an important clinical role. We enhance the active contours without edges model of Chan and Vese to account for the ACF's particular structure. We employ level sets to represent the segmentation boundaries and discretize in space by finite elements and in (artificial) time by finite differences. The approach is able to identify the ACF, their boundaries, and some of the internal crypts' orifices.
AB - The aim of this paper is to introduce a variational image segmentation method for assessing the aberrant crypt foci (ACF) in the human colon captured in vivo by endoscopy. ACF are thought to be precursors for colorectal cancer, and therefore their early detection may play an important clinical role. We enhance the active contours without edges model of Chan and Vese to account for the ACF's particular structure. We employ level sets to represent the segmentation boundaries and discretize in space by finite elements and in (artificial) time by finite differences. The approach is able to identify the ACF, their boundaries, and some of the internal crypts' orifices.
KW - Active contours
KW - Endoscopic images
KW - Image segmentation
KW - Level sets
UR - http://www.scopus.com/inward/record.url?scp=77950438513&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=77950438513&partnerID=8YFLogxK
U2 - 10.1109/TMI.2009.2036258
DO - 10.1109/TMI.2009.2036258
M3 - Article
C2 - 19923042
AN - SCOPUS:77950438513
SN - 0278-0062
VL - 29
SP - 998
EP - 1011
JO - IEEE Transactions on Medical Imaging
JF - IEEE Transactions on Medical Imaging
IS - 4
M1 - 5338023
ER -