Visualization of 3D high speed ultrahigh resolution optical coherence tomographic data identifies structures visible in 2D frames

Larry Kagemann, Hiroshi Isikawa, Gadi Wollstein, Michelle Gabriele, Joel S. Schuman

    Research output: Contribution to journalArticle

    Abstract

    Optical coherence tomography has allowed unprecedented visualization of ocular structures, but the identity of some visible objects within slices remains unknown. This study reconstructs a number of those objects in 3D space, allowing their identification by observation of their 3D morphology. In the case mottling deep within image slices through the optic disc, C-mode imaging provided visualization of the appearance and distribution of laminar pores. In the case of white spots and streaks sometimes observed in image slices through the cornea, C-mode imaging contoured to the path of those white spots allowed their visual identification as nerves extending radially into the cornea from the limbus. White spots observed in ultrahigh resolution retinal image slices were identified as blood within retinal capillaries. C-mode contour-corrected imaging of three-dimensional structures provided the identification of previously unidentified structures visible in cross-sectional image slices.

    Original languageEnglish (US)
    Pages (from-to)4208-4220
    Number of pages13
    JournalOptics Express
    Volume17
    Issue number5
    DOIs
    StatePublished - Mar 2 2009

    ASJC Scopus subject areas

    • Atomic and Molecular Physics, and Optics

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