VISUALIZING CLOTS ON ARTIFICIAL SURFACES.

Larry V. McIntire, Jeffrey A. Hubbell

Research output: Contribution to specialist publicationArticle

Abstract

The most serious problem remaining in the development of biomaterials for artificial organs is that artificial surfaces tend to encourage the formation of clots. These aggregates of platelets and leukocytes travel downstream and can lodge in the microcirculation of vital organs, decreasing the oxygen supply of local tissues and killing them. The authors developed a technique employing epifluorescent video microscopy and digital image processing to visualize and quantify the dynamics of blood/surface interactions under conditions of controlled flow.

Original languageEnglish (US)
Pages32-35
Number of pages4
Volume108
No1
Specialist publicationMechanical Engineering
StatePublished - Jan 1986

ASJC Scopus subject areas

  • Mechanical Engineering

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