Volumetric interactions in the statistical physics of biopolymers

A. Yu Grosberg, Ye I. Shakhnovich

    Research output: Contribution to journalArticlepeer-review


    A short review is presented of the development of the notions of the statistical physics of biological macromolecules and its current status. Attention is focussed on analysis of the manifestation of scale invariance and the fractal properties of biopolymers-DNA and proteins. The phase transitions associated with the tertiary structure of DNA are briefly analysed. The phase transitions in globular proteins, including the problem of denaturing, the two phases of the melted globule and the theory of heteropolymers are examined in greater detail. Some unresolved problems in this field and its prospects are discussed.

    Original languageEnglish (US)
    Pages (from-to)1031-1044
    Number of pages14
    Issue number6
    StatePublished - 1987

    ASJC Scopus subject areas

    • Biophysics


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